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FOLR3 Antibody

CAT: 0223-57-159Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-159Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the folate receptor (FOLR) family, members of which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This gene includes two polymorphic variants; the shorter one has two base deletion in the CDS, resulting in a truncated polypeptide, compared to the longer one. Both protein products are constitutively secreted in hematopoietic tissues and are potential serum marker for certain hematopoietic malignancies. The longer protein has a 71% and 79% sequence homology with the FOLR1 and FOLR2 proteins, respectively.
NCBI Gene ID
2352
Swiss Prot
P41439
Accession Number
P41439
Host
Rabbit
Reactivity
Human
Immunogen
This FOLR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human FOLR3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FOLR3
NCBI Official Name
Folate receptor gamma
NCBI Organism
Homo sapiens
Background Reference 01
O'Byrne, M.R., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (8) :689-694 (2010)
Background Reference 02
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 03
Boyles, A.L., et al. Genet. Epidemiol. 33 (3) :247-255 (2009)
Background Reference 04
Franke, B., et al. Birth Defects Res. PartClin. Mol. Teratol. 85 (3) :216-226 (2009)
Other Product Names
Folate receptor gamma, FR-gamma, Folate receptor 3, FOLR3
Tested Applications
WB
Protein ID
1169723
Physical Properties
Liquid

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