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MCOLN1 Antibody

CAT: 0223-57-113Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-113Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca (2+), Fe (2+), Na (+), K (+), and H (+), and is modulated by changes in Ca (2+) concentration. Mutations in this gene result in mucolipidosis type IV.
NCBI Gene ID
57192
Swiss Prot
Q9GZU1
Accession Number
Q9GZU1
Host
Rabbit
Reactivity
Human
Immunogen
This MCOLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the C-terminal region of human MCOLN1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
65 kDa
Fragment
Rabbit Ig
Symbol
MCOLN1
NCBI Official Name
Mucolipin-1
NCBI Organism
Homo sapiens
Background Reference 01
Eichelsdoerfer, J.L., et al. J. Biol. Chem. 285 (45) :34304-34308 (2010)
Background Reference 02
Curcio-Morelli, C., et al. J. Cell. Physiol. 222 (2) :328-335 (2010)
Background Reference 03
Vergarajauregui, S., et al. J. Biol. Chem. 284 (52) :36357-36366 (2009)
Background Reference 04
Ballif, B.A., et al. Mol. Cell Proteomics 3 (11) :1093-1101 (2004)
Other Product Names
Mucolipin-1, MG-2, Mucolipidin, MCOLN1, ML4
Tested Applications
WB, IHC-P
Protein ID
50401163
Physical Properties
Liquid

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