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PHF5A Antibody

CAT: 0223-57-082Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-082Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP) . The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes.
NCBI Gene ID
84844
Swiss Prot
Q7RTV0
Accession Number
Q7RTV0
Host
Rabbit
Reactivity
Human
Immunogen
This PHF5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the C-terminal region of human PHF5A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
12 kDa
Fragment
Rabbit Ig
Symbol
PHF5A
NCBI Official Name
PHD finger-like domain-containing protein 5A
NCBI Organism
Homo sapiens
Background Reference 01
Kuwasako, K., et al. Proteins 71 (4) :1617-1636 (2008)
Background Reference 02
Will, C.L., et al. RNA 10 (6) :929-941 (2004)
Background Reference 03
Collins, J.E., et al. Genome Biol. (10), R84 (2004) :
Background Reference 04
Will, C.L., et al. EMBO J. 21 (18) :4978-4988 (2002)
Other Product Names
PHD finger-like domain-containing protein 5A, PHD finger-like domain protein 5A, Splicing factor 3B-associated 14 kDa protein, SF3b14b, PHF5A
Tested Applications
WB, Flow
Protein ID
46577625
Physical Properties
Liquid

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