PHF5A Antibody

• Background:

  This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP) . The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes.

• NCBI Gene ID:

  84844

• Swiss Prot:

  Q7RTV0

• Accession Number:

  Q7RTV0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PHF5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the C-terminal region of human PHF5A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  12 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PHF5A

• NCBI Official Name:

  PHD finger-like domain-containing protein 5A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kuwasako, K., et al. Proteins 71 (4) :1617-1636 (2008)

• Background Reference 02:

  Will, C.L., et al. RNA 10 (6) :929-941 (2004)

• Background Reference 03:

  Collins, J.E., et al. Genome Biol. (10), R84 (2004) :

• Background Reference 04:

  Will, C.L., et al. EMBO J. 21 (18) :4978-4988 (2002)

• Other Product Names:

  PHD finger-like domain-containing protein 5A, PHD finger-like domain protein 5A, Splicing factor 3B-associated 14 kDa protein, SF3b14b, PHF5A

• Tested Applications:

  WB, Flow

• Protein ID:

  46577625

• Physical Properties:

  Liquid