PTPLA Antibody

CAT: 0223-57-074Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-074Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation.
NCBI Gene ID
9200
Swiss Prot
B0YJ81
Accession Number
B0YJ81
Host
Rabbit
Reactivity
Human
Immunogen
This PTPLA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PTPLA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Symbol
PTPLA
NCBI Official Name
Very-long-chain (3R) -3-hydroxyacyl-CoA dehydratase 1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 03
Liang, X., et al. Hum. Mutat. 30 (3) :463-471 (2009)
Background Reference 04
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Other Product Names
Very-long-chain (3R) -3-hydroxyacyl-CoA dehydratase 1, 3-hydroxyacyl-CoA dehydratase 1, HACD1, Cementum attachment protein, Protein-tyrosine phosphatase-like member A, PTPLA, HACD1
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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