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HJURP Antibody

CAT: 0223-57-033Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-033Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HJURP is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Directly binds Holliday junctions.
NCBI Gene ID
55355
Swiss Prot
Q8NCD3
Accession Number
Q8NCD3
Host
Rabbit
Reactivity
Human
Immunogen
This HJURP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 559-588 amino acids from the C-terminal region of human HJURP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
84 kDa
Fragment
Rabbit Ig
Symbol
HJURP
NCBI Official Name
Holliday junction recognition protein
NCBI Organism
Homo sapiens
Background Reference 01
Sebastiani, P., et al. Science (2010) In press :
Background Reference 02
Shuaib, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (4) :1349-1354 (2010)
Background Reference 03
Hu, Z., et al. Breast Cancer Res. 12 (2), R18 (2010) :
Background Reference 04
Dunleavy, E.M., et al. Cell 137 (3) :485-497 (2009)
Other Product Names
Holliday junction recognition protein, 14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated in lung cancer 9, HJURP
Tested Applications
WB, IHC-P, Flow
Protein ID
239938642
Physical Properties
Liquid

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