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ELAVL3 Antibody

CAT: 0223-56-996Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-996Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
NCBI Gene ID
1995
Swiss Prot
Q14576
Accession Number
Q14576
Host
Rabbit
Reactivity
Human
Immunogen
This ELAVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human ELAVL3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
40 kDa
Fragment
Rabbit Ig
Symbol
ELAVL3
NCBI Official Name
ELAV-like protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Behrends, U., et al. Int. J. Cancer 100 (6) :669-677 (2002)
Background Reference 02
Park, S., et al. Mol. Cell. Biol. 20 (13) :4765-4772 (2000)
Background Reference 03
King, P.H. Nucleic Acids Res. 28 (7), E20 (2000) :
Background Reference 04
Sakai, K., et al. Biochem. Biophys. Res. Commun. 256 (2) :263-268 (1999)
Other Product Names
ELAV-like protein 3, Hu-antigen C, HuC, Paraneoplastic cerebellar degeneration-associated antigen, Paraneoplastic limbic encephalitis antigen 21, ELAVL3, HUC, PLE21
Tested Applications
WB, IHC-P
Protein ID
21264436
Physical Properties
Liquid

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