SGEF Antibody

• Background :

  SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.

• NCBI Gene ID :

  26084

• Swiss Prot :

  Q96DR7

• Accession Number :

  Q96DR7

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This SGEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human SGEF.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  97 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  ARHGEF26

• NCBI Official Name :

  Rho guanine nucleotide exchange factor 26

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Yamada, S., et al. Oncogene 23 (35) :5901-5911 (2004)

• Background Reference 02 :

  Ellerbroek, S.M., et al. Mol. Biol. Cell 15 (7) :3309-3319 (2004)

• Background Reference 03 :

  Qi, H., et al. Endocrinology 144 (5) :1742-1752 (2003)

• Other Product Names :

  Rho guanine nucleotide exchange factor 26, SH3 domain-containing guanine exchange factor, ARHGEF26, SGEF

• Tested Applications :

  WB, IHC-P

• Protein ID :

  317373555

• Physical Properties :

  Liquid