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SGEF Antibody

CAT: 0223-56-989Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-989Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
NCBI Gene ID
26084
Swiss Prot
Q96DR7
Accession Number
Q96DR7
Host
Rabbit
Reactivity
Human
Immunogen
This SGEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human SGEF.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
97 kDa
Fragment
Rabbit Ig
Symbol
ARHGEF26
NCBI Official Name
Rho guanine nucleotide exchange factor 26
NCBI Organism
Homo sapiens
Background Reference 01
Yamada, S., et al. Oncogene 23 (35) :5901-5911 (2004)
Background Reference 02
Ellerbroek, S.M., et al. Mol. Biol. Cell 15 (7) :3309-3319 (2004)
Background Reference 03
Qi, H., et al. Endocrinology 144 (5) :1742-1752 (2003)
Other Product Names
Rho guanine nucleotide exchange factor 26, SH3 domain-containing guanine exchange factor, ARHGEF26, SGEF
Tested Applications
WB, IHC-P
Protein ID
317373555
Physical Properties
Liquid

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