AMELX Antibody

• Background:

  This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms.

• NCBI Gene ID:

  265

• Swiss Prot:

  Q99217

• Accession Number:

  Q99217

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This AMELX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human AMELX.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  22 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  AMELX

• NCBI Official Name:

  Amelogenin, X isoform

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Almqvist, S., et al.Mater Sci Mater Med 21 (3) :947-954 (2010)

• Background Reference 03:

  Lee, S.K., et al. J. Dent. Res. 89 (1) :46-50 (2010)

• Background Reference 04:

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Other Product Names:

  Amelogenin, X isoform, AMELX, AMG, AMGX

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  1168430

• Physical Properties:

  Liquid