REPS2 Antibody

• Background:

  The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  9185

• Swiss Prot:

  Q8NFH8

• Accession Number:

  Q8NFH8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This REPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the N-terminal region of human REPS2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  72 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  REPS2

• NCBI Official Name:

  RalBP1-associated Eps domain-containing protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Doolan, P., et al. Tumour Biol. 30 (4) :200-209 (2009) Singhal, S.S., et al. J. Biol. Chem. 283 (28) :19714-19729 (2008) Yadav, S., et al. Biochem. Biophys. Res. Commun. 328 (4) :1003-1009 (2005) Oosterhoff, J.K., et al. Int. J. Cancer 113 (4) :561-567 (2005) Penninkhof, F., et al. Oncogene 23 (33) :5607-5615 (2004)

• Other Product Names:

  RalBP1-associated Eps domain-containing protein 2, Partner of RalBP1, RalBP1-interacting protein 2, REPS2, POB1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  34098575

• Physical Properties:

  Liquid