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PFDN5 Antibody

CAT: 0223-56-862Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-862Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq].
NCBI Gene ID
5204
Swiss Prot
Q99471
Accession Number
Q99471
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PFDN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the Central region of human PFDN5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
17 kDa
Fragment
Rabbit Ig
Symbol
PFDN5
NCBI Official Name
Prefoldin subunit 5
NCBI Organism
Homo sapiens
Background Reference 01
Ma, H.C., et al. J. Biomed. Sci. 15 (4) :417-425 (2008)
Background Reference 02
Yoshida, T., et al. Exp. Cell Res. 314 (6) :1217-1228 (2008)
Background Reference 03
Lubyova, B., et al. J. Biol. Chem. 282 (44) :31944-31953 (2007)
Background Reference 04
Hagio, Y., et al. J. Cell. Biochem. 97 (1) :145-155 (2006)
Other Product Names
Prefoldin subunit 5, C-Myc-binding protein Mm-1, Myc modulator 1, PFDN5, MM1, PFD5
Tested Applications
WB, IHC-P
Protein ID
12231038
Physical Properties
Liquid

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