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KCNV2 Antibody

CAT: 0223-56-841Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-841Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.
NCBI Gene ID
169522
Swiss Prot
Q8TDN2
Accession Number
Q8TDN2
Host
Rabbit
Reactivity
Human
Immunogen
This KCNV2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-507 amino acids from the C-terminal region of human KCNV2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
62 kDa
Fragment
Rabbit Ig
Symbol
KCNV2
NCBI Official Name
Potassium voltage-gated channel subfamily V member 2
NCBI Organism
Homo sapiens
Background Reference 01
Robson, A.G., et al. Retina (Philadelphia, Pa.) 30 (1) :51-62 (2010)
Background Reference 02
Ben Salah, S., et al. Am. J. Ophthalmol. 145 (6) :1099-1106 (2008)
Background Reference 03
Wissinger, B., et al. Invest. Ophthalmol. Vis. Sci. 49 (2) :751-757 (2008)
Background Reference 04
Thiagalingam, S., et al. Ophthalmic Genet. 28 (3) :135-142 (2007)
Other Product Names
Potassium voltage-gated channel subfamily V member 2, Voltage-gated potassium channel subunit Kv82, KCNV2
Tested Applications
WB, IHC-P
Protein ID
26006804
Physical Properties
Liquid

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