ERLIN1 Antibody

• Background:

  Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) .

• NCBI Gene ID:

  10613

• Swiss Prot:

  O75477

• Accession Number:

  O75477

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ERLIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244-273 amino acids from the Central region of human ERLIN1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ERLIN1

• NCBI Official Name:

  Erlin-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Martins-de-Souza, D., et al.Psychiatr Res (2010) In press :

• Background Reference 03:

  Wang, Y., et al. Biochim. Biophys. Acta 1793 (11) :1710-1718 (2009)

• Background Reference 04:

  Pearce, M.M., et al. J. Biol. Chem. 284 (16) :10433-10445 (2009)

• Other Product Names:

  Erlin-1, Endoplasmic reticulum lipid raft-associated protein 1, Protein KE04, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1, SPFH domain-containing protein 1, ERLIN1, C10orf69, KE04, KEO4, SPFH1

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid