ATAD2 Antibody

• Background:

  A large family of ATPases has been described, whose key feature is that they share a conserved region of about 220 amino acids that contains an ATP-binding site. The proteins that belong to this family either contain one or two AAA (ATPases Associated with diverse cellular Activities) domains. AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes. The protein encoded by this gene contains two AAA domains, as well as a bromodomain.

• NCBI Gene ID:

  29028

• Swiss Prot:

  Q6PL18

• Accession Number:

  Q6PL18

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ATAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the N-terminal region of human ATAD2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  159 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ATAD2

• NCBI Official Name:

  ATPase family AAA domain-containing protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Revenko, A.S., et al. Mol. Cell. Biol. 30 (22) :5260-5272 (2010)

• Background Reference 02:

  Ciro, M., et al. Cancer Res. 69 (21) :8491-8498 (2009)

• Background Reference 03:

  Zou, J.X., et al. Cancer Res. 69 (8) :3339-3346 (2009)

• Background Reference 04:

  Zou, J.X., et al. Proc. Natl. Acad. Sci. U.S.A. 104 (46) :18067-18072 (2007)

• Other Product Names:

  ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated protein, ANCCA, ATAD2

• Tested Applications:

  WB

• Protein ID:

  74762365

• Physical Properties:

  Liquid