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MPO Antibody

CAT: 0223-56-822Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-822Size:400 µL
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Background
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq].
NCBI Gene ID
4353
Swiss Prot
P05164
Accession Number
P05164
Host
Rabbit
Reactivity
Human
Immunogen
This MPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-575 amino acids from the C-terminal region of human MPO.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
84 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MPO
NCBI Official Name
Myeloperoxidase
NCBI Organism
Homo sapiens
Background Reference 01
Banerjee, M., et al. Toxicol. Appl. Pharmacol. 249 (1) :47-54 (2010)
Background Reference 02
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 03
Nahon, P., et al. Antioxid. Redox Signal. (2010) In press :
Background Reference 04
Wang, Y., et al. J. Huazhong Univ. Sci. Technol. Med. Sci. 30 (4) :437-442 (2010)
Other Product Names
Myeloperoxidase, MPO, Myeloperoxidase, 89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain, MPO
Tested Applications
WB
Protein ID
129825
Physical Properties
Liquid

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