CCNI Antibody

• Background:

  The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined.

• NCBI Gene ID:

  10983

• Swiss Prot:

  Q14094

• Accession Number:

  Q14094

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CCNI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-331 amino acids from the C-terminal region of human CCNI.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CCNI

• NCBI Official Name:

  Cyclin-I

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sun, Z.L., et al. Biochim. Biophys. Acta 1774 (6) :764-771 (2007)

• Background Reference 02:

  Zhu, X., et al. Biochem. Biophys. Res. Commun. 249 (1) :56-60 (1998)

• Background Reference 03:

  Nakamura, T., et al. Exp. Cell Res. 221 (2) :534-542 (1995)

• Other Product Names:

  Cyclin-I, CCNI

• Tested Applications:

  WB

• Protein ID:

  9296954

• Physical Properties:

  Liquid