UQCRB Antibody

• Background :

  This gene encodes a protein which is part of the ubiquinol-cytochrome c oxidoreductase complex which contains ten nuclear-encoded and one mitochondrial-encoded subunits. The encoded protein binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. Mutations in this gene are associated with mitochondrial complex III deficiency. A pseudogene has been described on the X chromosome.

• NCBI Gene ID :

  7381

• Swiss Prot :

  P14927

• Accession Number :

  P14927

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This UQCRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the Central region of human UQCRB.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  14 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  UQCRB

• NCBI Official Name :

  Cytochrome b-c1 complex subunit 7

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17 (12) :3558-3566 (2008)

• Background Reference 02 :

  Haut, S., et al. Hum. Genet. 113 (2) :118-122 (2003)

• Background Reference 03 :

  Malaney, S., et al. Cytogenet. Cell Genet. 73 (4) :297-299 (1996)

• Background Reference 04 :

  Suzuki, H., et al. J. Biol. Chem. 265 (14) :8159-8163 (1990)

• Other Product Names :

  Cytochrome b-c1 complex subunit 7, Complex III subunit 7, Complex III subunit VII, QP-C, Ubiquinol-cytochrome c reductase complex 14 kDa protein, UQCRB, UQBP

• Tested Applications :

  WB, IHC-P

• Protein ID :

  136717

• Physical Properties :

  Liquid