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LARP7 Antibody

CAT: 0223-56-783Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-783Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LARP7 is a negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
NCBI Gene ID
51574
Swiss Prot
Q4G0J3
Accession Number
Q4G0J3
Host
Rabbit
Reactivity
Human
Immunogen
This LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the C-terminal region of human LARP7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
67 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LARP7
NCBI Official Name
La-related protein 7
NCBI Organism
Homo sapiens
Background Reference 01
Tyagi, M., et al. J. Virol. 84 (13) :6425-6437 (2010)
Background Reference 02
Kalsi, G., et al. Hum. Mol. Genet. 19 (12) :2497-2506 (2010)
Background Reference 03
Markert, A., et al. EMBO Rep. 9 (6) :569-575 (2008)
Background Reference 04
Krueger, B.J., et al. Nucleic Acids Res. 36 (7) :2219-2229 (2008)
Other Product Names
La-related protein 7, La ribonucleoprotein domain family member 7, P-TEFb-interaction protein for 7SK stability, PIP7S, LARP7
Tested Applications
WB
Protein ID
121945944
Physical Properties
Liquid

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