Products for Research Use Only

CHTF18 Antibody

CAT: 0223-56-780Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-780Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1; MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]) .
NCBI Gene ID
63922
Swiss Prot
Q8WVB6
Accession Number
Q8WVB6
Host
Rabbit
Reactivity
Human
Immunogen
This CHTF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 914-943 amino acids from the C-terminal region of human CHTF18.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
107 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CHTF18
NCBI Official Name
Chromosome transmission fidelity protein 18 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Murakami, T., et al. J. Biol. Chem. 285 (45) :34608-34615 (2010)
Background Reference 02
Farina, A., et al. J. Biol. Chem. 283 (30) :20925-20936 (2008)
Background Reference 03
Shiomi, Y., et al. J. Biol. Chem. 282 (29) :20906-20914 (2007)
Background Reference 04
Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)
Other Product Names
Chromosome transmission fidelity protein 18 homolog, hCTF18, CHL12, CHTF18, C16orf41, CTF18
Tested Applications
WB
Protein ID
74751544
Physical Properties
Liquid