CHTF18 Antibody

• Background:

  CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1; MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]) .

• NCBI Gene ID:

  63922

• Swiss Prot:

  Q8WVB6

• Accession Number:

  Q8WVB6

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CHTF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 914-943 amino acids from the C-terminal region of human CHTF18.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  107 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CHTF18

• NCBI Official Name:

  Chromosome transmission fidelity protein 18 homolog

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Murakami, T., et al. J. Biol. Chem. 285 (45) :34608-34615 (2010)

• Background Reference 02:

  Farina, A., et al. J. Biol. Chem. 283 (30) :20925-20936 (2008)

• Background Reference 03:

  Shiomi, Y., et al. J. Biol. Chem. 282 (29) :20906-20914 (2007)

• Background Reference 04:

  Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

• Other Product Names:

  Chromosome transmission fidelity protein 18 homolog, hCTF18, CHL12, CHTF18, C16orf41, CTF18

• Tested Applications:

  WB

• Protein ID:

  74751544

• Physical Properties:

  Liquid