Products for Research Use Only
RegisterLogin

RAP1A Antibody

CAT: 0223-56-753Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-56-753Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
NCBI Gene ID
5906
Swiss Prot
P62834
Accession Number
P62834
Host
Rabbit
Reactivity
Mouse
Immunogen
This RAP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-170 amino acids from the C-terminal region of human RAP1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat, Chicken, Zebrafish, Human, Monkey, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RAP1A
NCBI Official Name
Ras-related protein Rap-1A
NCBI Organism
Homo sapiens
Background Reference 01
Liu, C., et al. Mol. Cell. Biol. 30 (16) :3956-3969 (2010)
Background Reference 02
Kelly, P., et al. J. Biol. Chem. 285 (21) :15777-15785 (2010)
Background Reference 03
Ahmed, S.M., et al. J. Biol. Chem. 285 (9) :6538-6551 (2010)
Background Reference 04
Hsu, Y.H., et al. PLoS Genet. (6), E1000977 (2010) :
Other Product Names
Ras-related protein Rap-1A, C21KG, G-22K, GTP-binding protein smg p21A, Ras-related protein Krev-1, RAP1A, KREV1
Tested Applications
WB
Protein ID
51338607
Physical Properties
Liquid

Related Products

CatalogName
14-702RAP1B Antibody
58-039RAP1B Antibody
18-757RAP1B Antibody
18-738RAP2A Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody

Alternative Products

CatalogName
GWB-68B10CRAP1A Antibody

Popular Products