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GK Antibody

CAT: 0223-56-739Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-739Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of this gene belongs to the FGGY kinase family of proteins and encodes glycerol kinase. Glycerol kinase is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Defects in this gene are the cause of glycerol kinase deficiency (GKD) . Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
2710
Swiss Prot
P32189
Accession Number
P32189
Host
Rabbit
Reactivity
Human
Immunogen
This GK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human GK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Symbol
GK
NCBI Official Name
Glycerol kinase
NCBI Organism
Homo sapiens
Background Reference 01
Lu, Y., et al. J. Lipid Res. 49 (12) :2582-2589 (2008)
Background Reference 02
Zhang, Y.H., et al. Pediatr. Res. 59 (4 PT 1), 590-592 (2006) :
Background Reference 03
Ohira, R.H., et al. Biochem. Biophys. Res. Commun. 331 (1) :239-246 (2005)
Background Reference 04
Stepanian, S.V., et al. Mol. Genet. Metab. 80 (4) :412-418 (2003)
Other Product Names
Glycerol kinase, GK, Glycerokinase, ATP:glycerol 3-phosphotransferase, GK
Tested Applications
WB, IHC-P
Protein ID
205830913
Physical Properties
Liquid

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