SERPIND1 Antibody

• Background:

  This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.

• NCBI Gene ID:

  3053

• Swiss Prot:

  P05546

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 20-290 of human SERPIND1 (NP_000176.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 57-69kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  SERPIND1

• Positive Control 2:

  A-431

• Positive Control 3:

  HepG2

• Positive Control 4:

  293T

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse pancreas

• NCBI Official Name:

  Serpin family D member 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH1heparin cofactor 2, leuserpin 2, protease inhibitor leuserpin-2, serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1, serpin D1, serpin peptidase inhibitor, clade D (heparin cofactor), member 1

• Tested Applications:

  WB

• Physical Properties:

  Liquid