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GCDH Antibody

CAT: 0223-56-724Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-724Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO (2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
2639
Swiss Prot
Q92947
Accession Number
Q92947
Host
Rabbit
Reactivity
Human
Immunogen
This GCDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human GCDH.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
GCDH
NCBI Official Name
Glutaryl-CoA dehydrogenase, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Park, J.D., et al. J. Korean Med. Sci. 25 (6) :957-960 (2010)
Background Reference 03
Strauss, K.A., et al. Brain 133 (PT 1), 76-92 (2010) :
Background Reference 04
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Other Product Names
Glutaryl-CoA dehydrogenase, mitochondrial, GCD, GCDH
Tested Applications
WB, IHC-P
Protein ID
2492631
Physical Properties
Liquid

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