CBR3 Antibody

• Background:

  Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.

• NCBI Gene ID:

  874

• Swiss Prot:

  O75828

• Accession Number:

  O75828

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CBR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-224 amino acids from the C-terminal region of human CBR3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  31 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CBR3

• NCBI Official Name:

  Carbonyl reductase [NADPH] 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)

• Background Reference 02:

  Hosgood, H.D. III, et al. Respir Med 103 (12) :1866-1870 (2009)

• Background Reference 03:

  Zhang, J., et al. Pharm. Res. 26 (9) :2209-2215 (2009)

• Background Reference 04:

  Choi, J.Y., et al. Clin. Cancer Res. 15 (16) :5258-5266 (2009)

• Other Product Names:

  Carbonyl reductase [NADPH] 3, NADPH-dependent carbonyl reductase 3, CBR3

• Tested Applications:

  WB, Flow

• Physical Properties:

  Liquid