CBR4 Antibody

• Background:

  The heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) .

• NCBI Gene ID:

  84869

• Swiss Prot:

  Q8N4T8

• Accession Number:

  Q8N4T8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CBR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the C-terminal region of human CBR4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  25 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CBR4

• NCBI Official Name:

  Carbonyl reductase family member 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chen, Z., et al. FASEB J. 23 (11) :3682-3691 (2009)

• Background Reference 02:

  Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :

• Background Reference 03:

  Endo, S., et al. Biochem. Biophys. Res. Commun. 377 (4) :1326-1330 (2008)

• Background Reference 04:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Other Product Names:

  Carbonyl reductase family member 4, 1---, 3-oxoacyl-[acyl-carrier-protein] reductase, 111-, Quinone reductase CBR4, CBR4

• Tested Applications:

  WB

• Protein ID:

  269849708

• Physical Properties:

  Liquid