CBR4 Antibody

CAT: 0223-59-253Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-59-253Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) .
NCBI Gene ID
84869
Swiss Prot
Q8N4T8
Accession Number
Q8N4T8
Host
Rabbit
Reactivity
Human
Immunogen
This CBR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the C-terminal region of human CBR4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CBR4
NCBI Official Name
Carbonyl reductase family member 4
NCBI Organism
Homo sapiens
Background Reference 01
Chen, Z., et al. FASEB J. 23 (11) :3682-3691 (2009)
Background Reference 02
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :
Background Reference 03
Endo, S., et al. Biochem. Biophys. Res. Commun. 377 (4) :1326-1330 (2008)
Background Reference 04
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Other Product Names
Carbonyl reductase family member 4, 1---, 3-oxoacyl-[acyl-carrier-protein] reductase, 111-, Quinone reductase CBR4, CBR4
Tested Applications
WB
Protein ID
269849708
Physical Properties
Liquid

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