D SUMO Antibody

• Background:

  Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.

• NCBI Gene ID:

  33981

• Swiss Prot:

  O97102

• Accession Number:

  O97102

• Host:

  Rabbit

• Reactivity:

  Human, Drosophila

• Immunogen:

  This Drosophila SUMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the C-terminal region of human Drosophila SUMO.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  10 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  O97102

• NCBI Official Name:

  CG4494-PA

• NCBI Organism:

  Drosophila melanogaster

• Background Reference 01:

  Muller S, et al., Nat Rev Mol Cell Biol. 2001 2 (3) :202-10 Review.

• Background Reference 02:

  Hochstrasser M. Cell. 2001 107 (1) :5-8. Review.

• Background Reference 03:

  Kahyo T, et al., Mol Cell. 2001 Sep;8 (3) :713-8.

• Background Reference 04:

  Yeh ET, et al., Gene. 2000 May 2;248 (1-2) :1-14. Review.

• Other Product Names:

  CG4494-PA; LD07775p; Smt3; Ubiquitin-like protein SMT3

• Tested Applications:

  WB

• Physical Properties:

  Liquid