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PVRL3 Antibody

CAT: 0223-56-704Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-704Size:400 µL
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Background
Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559) . Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090) -catenin (see MIM 116805) system in epithelial cells.
NCBI Gene ID
25945
Swiss Prot
Q9NQS3
Accession Number
Q9NQS3
Host
Rabbit
Reactivity
Human
Immunogen
This PVRL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 507-536 amino acids from the C-terminal region of human PVRL3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PVRL3
NCBI Official Name
Nectin-3
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 03
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 04
Yu, X., et al. Nat. Immunol. 10 (1) :48-57 (2009)
Other Product Names
Nectin-3, CDw113, Poliovirus receptor-related protein 3, CD113, PVRL3, PRR3
Tested Applications
WB
Protein ID
74762752
Physical Properties
Liquid

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