DOC2A Antibody

• Background :

  There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca (2+) -dependent neurotransmitter release.

• NCBI Gene ID :

  8448

• Swiss Prot :

  Q14183

• Accession Number :

  Q14183

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This DOC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the Central region of human DOC2A.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  44 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  DOC2A

• NCBI Official Name :

  Double C2-like domain-containing protein alpha

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

• Background Reference 02 :

  Glessner, J.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (23) :10584-10589 (2010)

• Background Reference 03 :

  Guilmatre, A., et al. Arch. Gen. Psychiatry 66 (9) :947-956 (2009)

• Background Reference 04 :

  Kumar, R.A., et al. PLoS ONE (2), E4582 (2009) :

• Other Product Names :

  Double C2-like domain-containing protein alpha, Doc2, Doc2-alpha, DOC2A

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  150421541

• Physical Properties :

  Liquid