UNC45A Antibody

• Background:

  UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]) .

• NCBI Gene ID:

  55898

• Swiss Prot:

  Q9H3U1

• Accession Number:

  Q9H3U1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This UNC45A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-174 amino acids from the N-terminal region of human UNC45A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  103 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  UNC45A

• NCBI Official Name:

  Protein unc-45 homolog A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chadli, A., et al. J. Biol. Chem. 283 (15) :9509-9512 (2008)

• Background Reference 02:

  Bazzaro, M., et al. Am. J. Pathol. 171 (5) :1640-1649 (2007)

• Background Reference 03:

  Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

• Background Reference 04:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Other Product Names:

  Protein unc-45 homolog A, Unc-45A, GCUNC-45, Smooth muscle cell-associated protein 1, SMAP-1, UNC45A, SMAP1

• Tested Applications:

  WB

• Protein ID:

  74761419

• Physical Properties:

  Liquid