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UNC45A Antibody

CAT: 0223-56-678Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-678Size:400 µL
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Background
UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]) .
NCBI Gene ID
55898
Swiss Prot
Q9H3U1
Accession Number
Q9H3U1
Host
Rabbit
Reactivity
Human
Immunogen
This UNC45A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-174 amino acids from the N-terminal region of human UNC45A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
103 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
UNC45A
NCBI Official Name
Protein unc-45 homolog A
NCBI Organism
Homo sapiens
Background Reference 01
Chadli, A., et al. J. Biol. Chem. 283 (15) :9509-9512 (2008)
Background Reference 02
Bazzaro, M., et al. Am. J. Pathol. 171 (5) :1640-1649 (2007)
Background Reference 03
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 04
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Other Product Names
Protein unc-45 homolog A, Unc-45A, GCUNC-45, Smooth muscle cell-associated protein 1, SMAP-1, UNC45A, SMAP1
Tested Applications
WB
Protein ID
74761419
Physical Properties
Liquid

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