Unc93a Antibody

• Background :

  Unc93a Antibody: Unc93a, a human homolog of the C. elegans Unc93 gene, was initially identified by the sequencing of chromosome 6q27 at D6S193 as loss at this region correlated with sporadic ovarian cancer. Further analysis however, showed no tumor suppressor role for Unc93a. Unlike Unc93b, another homolog of the C. elegans Unc93 gene that is crucial for Toll-like receptor (TLR) signaling, the function of Unc93a is unknown. It is expressed in testis, small intestine, spleen, prostate and ovary.

• NCBI Gene ID :

  54346

• Swiss Prot :

  Q86WB7

• Accession Number :

  AAH99718

• Host :

  Rabbit

• Reactivity :

  Human

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Homeostasis

• Purification :

  Unc93a Antibody is affinity chromatography purified via peptide column.

• Positive Control :

  Cat. No. 1201 - HeLa Cell Lysate

• Concentration :

  1 mg/mL

• Buffer :

  Unc93a Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Unc93a antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment :

  IgG

• Specificity :

  Two isoforms of Unc93a are known to exist. This antibody will not cross-react with Unc93b.

• Symbol :

  UNC93A

• NCBI Official Name :

  Unc-93 homolog A (C. elegans)

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Liu Y, Dodds P, Emilion G, et al. The human homolog of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer. BioMed Central Genetics2002; 3:20.

• Background Reference 02 :

  Massey DC and Parkes M. Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy2007; 3:649-51.

• Other Product Names :

  Unc93a Antibody: Unc-93A, dJ366N23.1, dJ366N23.2, Protein unc-93 homolog A, HmUnc-93A

• Tested Applications :

  ELISA, WB

• Protein ID :

  71043465

• Physical Properties :

  Liquid