Products for Research Use Only
RegisterLogin

SPAG8 Antibody

CAT: 0223-56-675Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-56-675Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.
NCBI Gene ID
26206
Swiss Prot
Q99932
Accession Number
Q99932
Host
Rabbit
Reactivity
Human
Immunogen
This SPAG8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-411 amino acids from the C-terminal region of human SPAG8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SPAG8
NCBI Official Name
Sperm-associated antigen 8
NCBI Organism
Homo sapiens
Background Reference 01
Wu, H., et al. FEBS Lett. 584 (13) :2807-2815 (2010)
Background Reference 02
Li, R., et al. Cell Biochem. Funct. 27 (5) :264-268 (2009)
Background Reference 03
Cheng, G.Y., et al. Asian J. Androl. 9 (1) :23-29 (2007)
Background Reference 04
Tang, X., et al. J. Mol. Med. 82 (6) :383-388 (2004)
Other Product Names
Sperm-associated antigen 8, HSD-1, Sperm membrane protein 1, SMP-1, Sperm membrane protein BS-84, SPAG8
Tested Applications
WB
Protein ID
62511128
Physical Properties
Liquid

Related Products

CatalogName
62-012SPAG1 Antibody
22-234SPAG5 Antibody
18-936SPAG6 Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody

Alternative Products

CatalogName
70R-2385SPAG8 antibody

Popular Products