SMCP Antibody

• Background:

  Sperm mitochondria differ in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially to form a helical coiled sheath in the midpiece of the sperm flagellum. The protein encoded by this gene localizes to the capsule associated with the mitochondrial outer membranes and is thought to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath.

• NCBI Gene ID:

  4184

• Swiss Prot:

  P49901

• Accession Number:

  P49901

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SMCP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from the C-terminal region of human SMCP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  13 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SMCP

• NCBI Official Name:

  Sperm mitochondrial-associated cysteine-rich protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yatsenko, A.N., et al. Hum. Mol. Genet. 15 (23) :3411-3419 (2006)

• Background Reference 02:

  Hawthorne, S.K., et al. Genomics 87 (3) :382-391 (2006)

• Background Reference 03:

  Behne, D., et al. Annu. Rev. Nutr. 21, 453-473 (2001) :

• Background Reference 04:

  Cataldo, L., et al. Mol. Reprod. Dev. 45 (3) :320-331 (1996)

• Other Product Names:

  Sperm mitochondrial-associated cysteine-rich protein, SMCP, MCS, MCSP

• Tested Applications:

  WB

• Physical Properties:

  Liquid