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HRC Antibody

CAT: 0223-56-609Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-609Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a luminal sarcoplasmic reticulum protein identified by its ability to bind low-density lipoprotein with high affinity. The protein interacts with the cytoplasmic domain of triadin, the main transmembrane protein of the junctional sarcoplasmic reticulum (SR) of skeletal muscle. The protein functions in the regulation of releasable calcium into the SR.
NCBI Gene ID
3270
Swiss Prot
P23327
Accession Number
P23327
Host
Rabbit
Reactivity
Human
Immunogen
This HRC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the Central region of human HRC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
80 kDa
Fragment
Rabbit Ig
Symbol
HRC
NCBI Official Name
Sarcoplasmic reticulum histidine-rich calcium-binding protein
NCBI Organism
Homo sapiens
Background Reference 01
Arvanitis, D.A., et al. Eur. Heart J. 29 (20) :2514-2525 (2008)
Background Reference 02
Arvanitis, D.A., et al. Am. J. Physiol. Heart Circ. Physiol. 293 (3), H1581-H1589 (2007) :
Background Reference 03
Fan, G.C., et al. Am. J. Physiol. Heart Circ. Physiol. 287 (4), H1705-H1711 (2004) :
Background Reference 04
Anderson, J.P., et al. Mol. Cell. Biol. 24 (9) :3757-3768 (2004)
Other Product Names
Sarcoplasmic reticulum histidine-rich calcium-binding protein, HRC, HCP
Tested Applications
WB, IHC-P
Protein ID
134873
Physical Properties
Liquid

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