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IFNGR1 Antibody

CAT: 0223-56-568Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-568Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq].
NCBI Gene ID
3459
Swiss Prot
P15260
Accession Number
P15260
Host
Rabbit
Reactivity
Human
Immunogen
This IFNGR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 463-489 amino acids from the C-terminal region of human IFNGR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
IFNGR1
NCBI Official Name
Interferon gamma receptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Silva, L.K., et al. Eur. J. Hum. Genet. 18 (11) :1221-1227 (2010)
Background Reference 02
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 03
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Background Reference 04
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Other Product Names
Interferon gamma receptor 1, IFN-gamma receptor 1, IFN-gamma-R1, CDw119, CD119, IFNGR1
Tested Applications
WB
Protein ID
124474
Physical Properties
Liquid

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