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IFNGR2 Antibody

CAT: 0223-26-149Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-26-149Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IFNGR2 is the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
3460
Swiss Prot
P38484
Accession Number
NP_005525
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IFNGR2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IFNGR2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
35 kDa
Applications Notes
IFNGR2 antibody can be used for detection of IFNGR2 by ELISA at 1:62500. IFNGR2 antibody can be used for detection of IFNGR2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
IFNGR2
NCBI Official Name
Interferon gamma receptor 2 (interferon gamma transducer 1)
NCBI Organism
Homo sapiens
Background Reference 01
Jin, Y.H., (2008) Biochem. Biophys. Res. Commun. 368 (3), 690-695.
Other Product Names
IFNGR2, AF-1, IFGR2, IFNGT1
Tested Applications
ELISA, WB
Protein ID
47419934
Physical Properties
Liquid

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