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MED8 Antibody

CAT: 0223-56-565Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-565Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.
NCBI Gene ID
112950
Swiss Prot
Q96G25
Accession Number
Q96G25
Host
Rabbit
Reactivity
Human
Immunogen
This MED8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-122 amino acids from the Central region of human MED8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MED8
NCBI Official Name
Mediator of RNA polymerase II transcription subunit 8
NCBI Organism
Homo sapiens
Background Reference 01
Leonard, V.H., et al. J. Virol. 80 (19) :9667-9675 (2006)
Background Reference 02
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345 (3) :1022-1032 (2006)
Background Reference 03
Sato, S., et al. Mol. Cell 14 (5) :685-691 (2004)
Background Reference 04
Tomomori-Sato, C., et al. J. Biol. Chem. 279 (7) :5846-5851 (2004)
Other Product Names
Mediator of RNA polymerase II transcription subunit 8, Activator-recruited cofactor 32 kDa component, ARC32, Mediator complex subunit 8, MED8
Tested Applications
WB
Protein ID
31076772
Physical Properties
Liquid

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