CLDN2 Antibody

CAT: 0223-56-551Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-551Size:400 µL
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Background
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
NCBI Gene ID
9075
Swiss Prot
P57739
Accession Number
P57739
Host
Rabbit
Reactivity
Human
Immunogen
This CLDN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-201 amino acids from the C-terminal region of human CLDN2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Symbol
CLDN2
NCBI Official Name
Claudin-2
NCBI Organism
Homo sapiens
Background Reference 01
Smith, A.J., et al. J. Acquir. Immune Defic. Syndr. 55 (3) :306-315 (2010)
Background Reference 02
Kojima, F., et al. Oncol. Rep. 23 (4) :927-931 (2010)
Background Reference 03
Szakal, D.N., et al. Virchows Arch. 456 (3) :245-250 (2010)
Background Reference 04
Buchert, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (6) :2628-2633 (2010)
Other Product Names
Claudin-2, SP82, CLDN2
Tested Applications
WB, IHC-P, Flow
Protein ID
12229749
Physical Properties
Liquid

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