KERA Antibody

• Background:

  The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2) .

• NCBI Gene ID:

  11081

• Swiss Prot:

  O60938

• Accession Number:

  O60938

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KERA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the C-terminal region of human KERA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  41 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  KERA

• NCBI Official Name:

  Keratocan

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Aldave, A.J., et al. Invest. Ophthalmol. Vis. Sci. 51 (8) :4006-4012 (2010)

• Background Reference 02:

  Dimasi, D.P., et al. Mol. Vis. 16, 562-569 (2010) :

• Background Reference 03:

  Wheeler, H.E., et al. PLoS Genet. (10), E1000685 (2009) :

• Background Reference 04:

  Melrose, J., et al. Arthritis Res. Ther. 10 (4), R79 (2008) :

• Other Product Names:

  Keratocan, KTN, Keratan sulfate proteoglycan keratocan, KERA, SLRR2B

• Tested Applications:

  WB

• Physical Properties:

  Liquid