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UGDH Antibody

CAT: 0223-56-538Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-538Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
7358
Swiss Prot
O60701
Accession Number
O60701
Host
Rabbit
Reactivity
Human
Immunogen
This UGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human UGDH.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Symbol
UGDH
NCBI Official Name
UDP-glucose 6-dehydrogenase
NCBI Organism
Homo sapiens
Background Reference 01
Wang, T.P., et al. Exp. Cell Res. 316 (17) :2893-2902 (2010)
Background Reference 02
Hodgkinson, C.A., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (19) :8695-8700 (2010)
Background Reference 03
Huang, D., et al. Int. J. Cancer 126 (2) :315-327 (2010)
Background Reference 04
Lee, H.S., et al. Arch. Biochem. Biophys. 486 (1) :35-43 (2009)
Other Product Names
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH, UGDH
Tested Applications
WB, IHC-P
Physical Properties
Liquid

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MBS8500580-01UGDH Antibody

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