Products for Research Use Only
RegisterLogin

MLPH Antibody

CAT: 0223-56-536Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-56-536Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
NCBI Gene ID
79083
Swiss Prot
Q9BV36
Accession Number
Q9BV36
Host
Rabbit
Reactivity
Human
Immunogen
This MLPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-569 amino acids from the C-terminal region of human MLPH.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
66 kDa
Fragment
Rabbit Ig
Symbol
MLPH
NCBI Official Name
Melanophilin
NCBI Organism
Homo sapiens
Background Reference 01
Park, J.W., et al. J. Med. Genet. 43 (7) :598-608 (2006)
Background Reference 02
Seabra, M.C., et al. Traffic 5 (6) :393-399 (2004)
Background Reference 03
Fukuda, M., et al. J. Cell. Sci. 117 (PT 4), 583-591 (2004) :
Background Reference 04
Lukusa, T., et al. Genet. Couns. 15 (3) :293-301 (2004)
Other Product Names
Melanophilin, Exophilin-3, Slp homolog lacking C2 domains a, SlaC2-a, Synaptotagmin-like protein 2a, MLPH, SLAC2A
Tested Applications
WB, IHC-P
Protein ID
32129730
Physical Properties
Liquid

Related Products

CatalogName
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody
19-580FABP3 Antibody
15-580POMGNT2 Antibody
35-153Cytomegalovirus Antibody

Alternative Products

CatalogName
A28662-100UGMLPH Antibody

Popular Products