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ATP5J Antibody

CAT: 0223-56-437Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-437Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8) . This gene encodes the F6 subunit of the Fo complex, required for F1 and Fo interactions. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. A pseudogene exists on chromosome Yp11.
NCBI Gene ID
522
Swiss Prot
P18859
Accession Number
P18859
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
This ATP5J antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the Central region of human ATP5J.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
13 kDa
Fragment
Rabbit Ig
Symbol
ATP5J
NCBI Official Name
ATP synthase-coupling factor 6, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Osanai, T., et al. Cardiovasc. Res. 81 (4) :780-787 (2009)
Background Reference 02
Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17 (12) :3558-3566 (2008)
Background Reference 03
Kumagai, A., et al. Atherosclerosis 200 (1) :45-50 (2008)
Background Reference 04
Chai, S.B., et al. Circ. J. 71 (5) :693-697 (2007)
Other Product Names
ATP synthase-coupling factor 6, mitochondrial, ATPase subunit F6, ATP5J, ATP5A, ATPM
Tested Applications
WB, IHC-P, IF
Protein ID
114688
Physical Properties
Liquid

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