Dok5 Antibody

CAT: 0223-56-408Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-408Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
NCBI Gene ID
55816
Swiss Prot
Q9P104
Accession Number
Q9P104
Host
Rabbit
Reactivity
Human
Immunogen
This Dok5 antibody is generated from rabbits immunized with a recombinant protein (GST-tag removed) from human Dok5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DOK5
NCBI Official Name
Docking protein 5
NCBI Organism
Homo sapiens
Background Reference 01
Liu, X., et al.Am Acad Child Adolesc Psychiatry 49 (1) :33-41 (2010)
Background Reference 02
Tabassum, R., et al. BMC Med. Genet. 11, 35 (2010) :
Background Reference 03
Shi, L., et al. Cell. Signal. 18 (11) :1995-2003 (2006)
Background Reference 04
Cai, D., et al. J. Biol. Chem. 278 (28) :25323-25330 (2003)
Other Product Names
Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6, DOK5, C20orf180
Tested Applications
WB
Protein ID
26393190
Physical Properties
Liquid

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