FFAR1 Antibody

• Background:

  This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes.

• NCBI Gene ID:

  2864

• Swiss Prot:

  O14842

• Accession Number:

  O14842

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This FFAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-300 amino acids from the C-terminal region of human FFAR1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  31 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  FFAR1

• NCBI Official Name:

  Free fatty acid receptor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Lu, S.Y., et al. J. Mol. Graph. Model. 28 (8) :766-774 (2010)

• Background Reference 03:

  Del Guerra, S., et al. Nutr Metab Cardiovasc Dis 20 (1) :22-25 (2010)

• Background Reference 04:

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Other Product Names:

  Free fatty acid receptor 1, G-protein coupled receptor 40, FFAR1, GPR40

• Tested Applications:

  WB

• Physical Properties:

  Liquid