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SLC12A7 Antibody

CAT: 0223-56-393Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-393Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SLC12A7 mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K (+) uptake into Deiters' cells in the cochlea and contribute to K (+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl (-) extrusion in the kidney and contribute to renal acidification (By similarity) .
NCBI Gene ID
10723
Swiss Prot
Q9Y666
Accession Number
Q9Y666
Host
Rabbit
Reactivity
Human
Immunogen
This SLC12A7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the N-terminal region of human SLC12A7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
119 kDa
Fragment
Rabbit Ig
Symbol
SLC12A7
NCBI Official Name
Solute carrier family 12 member 7
NCBI Organism
Homo sapiens
Background Reference 01
Hartmann, A.M., et al. J. Biol. Chem. 285 (31) :23994-24002 (2010)
Background Reference 02
Kamatani, Y., et al. Nat. Genet. 42 (3) :210-215 (2010)
Background Reference 03
Chen, Y.F., et al. Cancer Res. 69 (22) :8585-8593 (2009)
Background Reference 04
Fujii, T., et al. J. Biol. Chem. 284 (1) :619-629 (2009)
Other Product Names
Solute carrier family 12 member 7, Electroneutral potassium-chloride cotransporter 4, K-Cl cotransporter 4, SLC12A7, KCC4
Tested Applications
WB, IHC-P
Protein ID
166202480
Physical Properties
Liquid

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