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SLC12A6 Antibody

CAT: 0223-56-387Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-387Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.
NCBI Gene ID
9990
Swiss Prot
Q9UHW9
Accession Number
Q9UHW9
Host
Rabbit
Reactivity
Human
Immunogen
This SLC12A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SLC12A6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
128 kDa
Fragment
Rabbit Ig
Symbol
SLC12A6
NCBI Official Name
Solute carrier family 12 member 6
NCBI Organism
Homo sapiens
Background Reference 01
Rinehart, J., et al. Cell 138 (3) :525-536 (2009)
Background Reference 02
Rudnik-Schoneborn, S., et al. Neuropediatrics 40 (3) :129-133 (2009)
Background Reference 03
De Krom, M., et al. Biol. Psychiatry 65 (7) :625-630 (2009)
Background Reference 04
Moser, D., et al. Neuropsychopharmacology 34 (2) :458-467 (2009)
Other Product Names
Solute carrier family 12 member 6, Electroneutral potassium-chloride cotransporter 3, K-Cl cotransporter 3, SLC12A6, KCC3
Tested Applications
WB, IHC-P
Protein ID
27151690
Physical Properties
Liquid

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