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POMT1 Antibody

CAT: 0223-56-386Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-386Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K) . Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
10585
Swiss Prot
Q9Y6A1
Accession Number
Q9Y6A1
Host
Rabbit
Reactivity
Human
Immunogen
This POMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-735 amino acids from the C-terminal region of human POMT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
85 kDa
Fragment
Rabbit Ig
Symbol
POMT1
NCBI Official Name
Protein O-mannosyl-transferase 1
NCBI Organism
Homo sapiens
Background Reference 01
Manya, H., et al. J. Biochem. 147 (3) :337-344 (2010)
Background Reference 02
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 03
Cotarelo, R.P., et al. Clin. Genet. 76 (1) :108-112 (2009)
Background Reference 04
Mercuri, E., et al. Neurology 72 (21) :1802-1809 (2009)
Other Product Names
Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1, POMT1
Tested Applications
WB, IHC-P, Flow
Protein ID
332278226
Physical Properties
Liquid

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