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MAD1L1 Antibody

CAT: 0223-56-363Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-363Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
NCBI Gene ID
8379
Swiss Prot
Q9Y6D9
Accession Number
Q9Y6D9
Host
Rabbit
Reactivity
Human
Immunogen
This MAD1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-151 amino acids from the N-terminal region of human MAD1L1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
83 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MAD1L1
NCBI Official Name
Mitotic spindle assembly checkpoint protein MAD1
NCBI Organism
Homo sapiens
Background Reference 01
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 02
Guo, Y., et al. J. Med. Genet. 47 (9) :616-622 (2010)
Background Reference 03
Wang, H.B., et al. J. Gastrointest. Surg. 14 (8) :1227-1234 (2010)
Background Reference 04
Hewitt, L., et al. J. Cell Biol. 190 (1) :25-34 (2010)
Other Product Names
Mitotic spindle assembly checkpoint protein MAD1, Mitotic arrest deficient 1-like protein 1, MAD1-like protein 1, Mitotic checkpoint MAD1 protein homolog, HsMAD1, hMAD1, Tax-binding protein 181, MAD1L1, MAD1, TXBP181
Tested Applications
WB
Protein ID
52783153
Physical Properties
Liquid

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