ACTN3 Antibody

• Background:

  Alpha-actinin is an actin-binding protein with multiple roles in different cell types. This gene expression is limited to skeletal muscle. It is localized to the Z-disc and analogous dense bodies, where it helps to anchor the myofibrillar actin filaments

• NCBI Gene ID:

  89

• Swiss Prot:

  Q08043

• Accession Number:

  Q08043

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ACTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-437 amino acids from the Central region of human ACTN3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  103 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ACTN3

• NCBI Official Name:

  Alpha-actinin-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rodriguez-Romo, G., et al. Eur. J. Appl. Physiol. 110 (6) :1099-1106 (2010)

• Background Reference 02:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 03:

  Berman, Y., et al. Physiology (Bethesda) 25 (4) :250-259 (2010)

• Background Reference 04:

  Ruiz, J.R., et al. ScandMed Sci Sports (2010) In press :

• Other Product Names:

  Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein, ACTN3

• Tested Applications:

  WB, IHC-P

• Protein ID:

  215273967

• Physical Properties:

  Liquid