Products for Research Use Only
RegisterLogin

F2RL2 Antibody

CAT: 0223-56-323Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-56-323Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.
NCBI Gene ID
2151
Swiss Prot
O00254
Accession Number
O00254
Host
Rabbit
Reactivity
Human
Immunogen
This F2RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human F2RL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Symbol
F2RL2
NCBI Official Name
Proteinase-activated receptor 3
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Popovic, M., et al. J. Thromb. Thrombolysis 30 (2) :164-171 (2010)
Background Reference 03
Van Laer, L., et al. Eur. J. Hum. Genet. 18 (6) :685-693 (2010)
Background Reference 04
Wysoczynski, M., et al. Mol. Cancer Res. 8 (5) :677-690 (2010)
Other Product Names
Proteinase-activated receptor 3, PAR-3, Coagulation factor II receptor-like 2, Thrombin receptor-like 2, F2RL2, PAR3
Tested Applications
WB, IHC-P
Physical Properties
Liquid

Related Products

CatalogName
23-606F2RL3 Antibody
23-725F2RL1 Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody
19-580FABP3 Antibody

Alternative Products

CatalogName
70R-32465F2RL2 antibody

Popular Products