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FOXN1 Antibody

CAT: 0223-56-203Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-203Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq].
NCBI Gene ID
8456
Swiss Prot
O15353
Accession Number
O15353
Host
Rabbit
Reactivity
Human
Immunogen
This FOXN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the Central region of human FOXN1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
69 kDa
Fragment
Rabbit Ig
Symbol
FOXN1
NCBI Official Name
Forkhead box protein N1
NCBI Organism
Homo sapiens
Background Reference 01
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 02
Mandinova, A., et al. J. Clin. Invest. 119 (10) :3127-3137 (2009)
Background Reference 03
Pignata, C., et al. Adv. Exp. Med. Biol. 665, 195-206 (2009) :
Background Reference 04
Weiner, L., et al. Cell 130 (5) :932-942 (2007)
Other Product Names
Forkhead box protein N1, Winged-helix transcription factor nude, FOXN1, RONU, WHN
Tested Applications
WB, Flow
Physical Properties
Liquid

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