PCDH1 Antibody

• Background:

  This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.

• NCBI Gene ID:

  5097

• Swiss Prot:

  Q08174

• Accession Number:

  Q08174

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PCDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the N-terminal region of human PCDH1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  115 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PCDH1

• NCBI Official Name:

  Protocadherin-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Koppelman, G.H., et al. Am. J. Respir. Crit. Care Med. 180 (10) :929-935 (2009)

• Background Reference 02:

  Rush, J., et al. Nat. Biotechnol. 23 (1) :94-101 (2005)

• Background Reference 03:

  Ballif, B.A., et al. Mol. Cell Proteomics 3 (11) :1093-1101 (2004)

• Background Reference 04:

  Ballif, B.A., et al. Mol. Cell Proteomics 3 (11) :1093-1101 (2004)

• Other Product Names:

  Protocadherin-1, Cadherin-like protein 1, Protocadherin-42, PC42, PCDH1

• Tested Applications:

  WB, IHC-P, IF

• Protein ID:

  215273864

• Physical Properties:

  Liquid